Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685796 | 1.00 | GRM2 (0.56) | GRM2HTR2AGBA1KCNH2MEN1 | |
| SCHEMBL5685811 | 1.00 | GRM2 (0.56) | GRM2HTR2AGBA1KCNH2MEN1 | |
| SCHEMBL5685784 | 0.90 | SIGMAR1 (0.51) | GRM2HTR2AKCNH2KMT2AAGTR2 | |
| SCHEMBL5686080 | 0.90 | SIGMAR1 (0.51) | GRM2HTR2AKCNH2KMT2AAGTR2 | |
| SCHEMBL1116547 | 0.90 | ALDH1A1 (0.56) | GRM2HTR2AHRH3OPRD1ALDH1A1 | |
| SCHEMBL2032734 | 0.90 | ALDH1A1 (0.56) | GRM2HTR2AHRH3OPRD1ALDH1A1 | |
| SCHEMBL2772130 | 0.83 | LTA4H (0.57) | HTR2AGBA1SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2772128 | 0.83 | LTA4H (0.57) | HTR2AGBA1SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2772367 | 0.83 | LTA4H (0.57) | HTR2AGBA1SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5367420 | 0.83 | GRM2 (0.58) | GRM2HTR2AGBA1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-1308519-B1 | Process for improving optical purity of azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | EP | disclosed |
| EP-1308519-A1 | Process for improving optical purity of azetidine-2-carboxylic acid | Sumitomo Chemical Company, Limited (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-0855446-B1 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6410279-B1 | GENERATING PREFERENTIAL COMPOUND IN SOLUTION; OBTAIN N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACID ESTER, INCUBATE WITH PREFERENTIAL ENZYME, RECOVER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6162621-A | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0855446-A2 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-07-29 | — | — | EP | disclosed |