Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP1 | P63208 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | GALR1 | P47211 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233751 | 0.90 | L3MBTL1 (0.66) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL5234323 | 0.89 | ABCB1 (0.56) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL5683408 | 0.88 | ABCB1 (0.60) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL5656725 | 0.87 | CHRNB2 (0.53) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL24848428 | 0.86 | ABCB1 (0.55) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL5682855 | 0.84 | MAPT (0.52) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL1458624 | 0.83 | L3MBTL1 (0.73) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL2385957 | 0.83 | ABCB1 (0.59) | MAPTLMNASMN1; SMN2ABCB1ALDH1A1 | |
| SCHEMBL29475535 | 0.83 | GPR119 (0.59) | MAPTLMNAABCB1ALDH1A1MEN1 | |
| SCHEMBL25317704 | 0.83 | GPR119 (0.59) | MAPTLMNAABCB1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645556-A1 | Arylpiperazine-benzoylamide derivatives useful as pharmaceutical agents | Boehringer Ingelheim International GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |