Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.47 |
| ▸ | DRD3 | P35462 | 8/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686598 | 1.00 | DRD2 (0.47) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL5683353 | 0.83 | SRD5A1 (0.44) | DRD2DRD3DRD4 | |
| SCHEMBL5683349 | 0.83 | SRD5A1 (0.44) | DRD2DRD3DRD4 | |
| SCHEMBL5684920 | 0.80 | PPIB (0.40) | — | |
| SCHEMBL5684916 | 0.80 | PPIB (0.40) | — | |
| SCHEMBL5686345 | 0.78 | DRD2 (0.46) | DRD2DRD3HTR1DAKR1C3 | |
| SCHEMBL5686342 | 0.78 | DRD2 (0.46) | DRD2DRD3HTR1DAKR1C3 | |
| SCHEMBL5684668 | 0.78 | PPARA (0.37) | AKR1C3 | |
| SCHEMBL5684671 | 0.78 | PPARA (0.37) | AKR1C3 | |
| SCHEMBL6158884 | 0.76 | DRD2 (0.58) | DRD2DRD3HTR1DDRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |