Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691355 | 0.90 | UGT2B7 (0.36) | UGT2B7MAPTPTGS1PTGS2KDM5A | |
| SCHEMBL5689177 | 0.79 | NAMPT (0.38) | MAPTTDP1CYP2C9ALDH1A1POLB | |
| SCHEMBL29193847 | 0.75 | KDM5A (0.53) | MAPTALOX5KDM5AKDM7AKDM4C | |
| SCHEMBL4612433 | 0.75 | — | — | |
| SCHEMBL1427280 | 0.72 | LMNA (0.39) | UGT2B7ALOX5TDP1ABL1IDE | |
| SCHEMBL2547053 | 0.70 | GAA (0.46) | UGT2B7MAPTALOX5ITGB3ITGA2B | |
| SCHEMBL3822434 | 0.70 | ALOX5 (0.40) | UGT2B7MAPTALOX5LMNACYP2C9 | |
| SCHEMBL3823436 | 0.70 | ALOX5 (0.40) | UGT2B7MAPTALOX5LMNACYP2C9 | |
| SCHEMBL11329424 | 0.69 | KDM5A (0.61) | MAPTKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL9013673 | 0.69 | ALOX5 (0.65) | MAPTALOX5KDM5AKDM7AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648526-A1 | CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTERS | Symrise GmbH & Co. KG (DE) | 2006-04-26 | — | — | EP | claimed |
| WO-2005009492-A1 | CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTERS | SYMRISE GMBH & CO. KG (DE) | 2005-02-03 | — | — | WO | claimed |
| EP-1648526-A1 | CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTERS | Symrise GmbH & Co. KG (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005009492-A1 | CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTERS | SYMRISE GMBH & CO. KG (DE) | 2005-02-03 | — | — | WO | disclosed |