SCHEMBL1427280

SCHEMBL1427280

CC1CCC(CCCC(=O)O)C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 4/20 0.39
ALOX5 P09917 1/20 0.39
PPARG P37231 7/20 0.38
ABL1 P00519 1/20 0.38
IDE P14735 1/20 0.38
RIN1 Q13671 1/20 0.38
NR2E3 Q9Y5X4 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
TSHR P16473 6/20 0.38
PMP22 Q01453 2/20 0.38
NFKB1 P19838 1/20 0.38
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP2C9 P11712 1/20 0.38
AKR1B1 P15121 1/20 0.38
UGT2B7 P16662 1/20 0.38
NR1I2 O75469 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17924014 0.81 MAPT (0.34) KMT2A
SCHEMBL2706111 0.81 ALOX5 (0.38) LMNATDP1ALOX5PPARGABL1
SCHEMBL5634431 0.77 GRM2 (0.39) CYP2C9
SCHEMBL4872290 0.75 CYP1A2 (0.37) LMNATDP1
SCHEMBL22789898 0.74
SCHEMBL2707175 0.74 UGT2B7 (0.40) LMNATDP1ALOX5TSHRPMP22
SCHEMBL1536541 0.73 LMNA (0.46) LMNATDP1ALOX5PPARGTSHR
SCHEMBL5688652 0.72 UGT2B7 (0.39) LMNATDP1ALOX5PPARGABL1
SCHEMBL4557205 0.72
SCHEMBL23533413 0.72 TSHR (0.48) LMNATDP1ALOX5PPARGTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384027-A1 COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR Firmenich SA (CH) 2024-06-19 EP claimed
EP-3766545-B1 ACTIVE AGENT FOR USE IN HAIR GROWTH REGULATION CUTANEON SKIN & HAIR INNOVATIONS GMBH (DE) 2023-08-16 EP claimed
WO-2023072604-A1 COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR FIRMENICH SA (CH) 2023-05-04 WO claimed
US-20220168206-A1 ACTIVE AGENT FOR USE IN HAIR GROWTH REGULATION CUTANEON - SKIN & HAIR INNOVATIONS GMBH (DE) 2022-06-02 US claimed
WO-2021009177-A1 ACTIVE AGENT FOR USE IN HAIR GROWTH REGULATION MONASTERIUM LABORATORY SKIN & HAIR RESEARCH SOLUTIONS GMBH (DE) 2021-01-21 WO claimed
EP-3766545-A1 ACTIVE AGENT FOR USE IN HAIR GROWTH REGULATION Monasterium Laboratory Skin & Hair Research Solutions GmbH (DE) 2021-01-20 EP claimed
US-9844224-B2 Bitter alkaloid containing consumables comprising bitter blockers GIVAUDAN SA (CH) 2017-12-19 US claimed
CN-103429098-B Odor masking 奇华顿股份有限公司 2016-08-31 CN claimed
EP-2685840-B1 OFF-NOTE MASKING GIVAUDAN SA (CH) 2016-05-18 EP claimed
EP-2685840-A1 OFF-NOTE MASKING Givaudan SA (CH) 2014-01-22 EP claimed
EP-2306851-B1 BITTER ALKALOID CONTAINING CONSUMABLES COMPRISING BITTER BLOCKERS GIVAUDAN SA (CH) 2012-08-01 EP claimed
EP-2139841-B1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2012-05-02 EP claimed
CN-102065707-A Bitter alkaloid-containing consumable product comprising a bitter blocker GIVAUDAN SA 2011-05-18 CN claimed
US-20110086138-A1 Bitter Alkaloid Containing Consumables Comprising Bitter Blockers GIVAUDAN SA (CH) 2011-04-14 US claimed
EP-2306851-A1 BITTER ALKALOID CONTAINING CONSUMABLES COMPRISING BITTER BLOCKERS Givaudan SA (CH) 2011-04-13 EP claimed
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-11-11 US claimed
EP-2139841-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS Givaudan SA (CH) 2010-01-06 EP claimed
WO-2009140784-A1 BITTER ALKALOID CONTAINING CONSUMABLES COMPRISING BITTER BLOCKERS GIVAUDAN SA (CH) 2009-11-26 WO claimed
WO-2008119197-A1 4-(2, 2, 3-TRIMETHYLCYCLOPENTYL) BUTANOIC ACID USED AS AN OFF-NOTE MASKING AGENT IN CONSUMABLES GIVAUDAN SA (CH) 2008-10-09 WO claimed
WO-2008119196-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-10-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS SORD, OTC, ASPH LMNA 3769/4885TDP1 4601/4885ALOX5 3721/4885
US-20110086138-A1 Bitter Alkaloid Containing Consumables Comprising Bitter Blockers TAS2R8, TAS2R5, TAS2R1 LMNA 4179/4885TDP1 1210/4885ALOX5 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.