Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386080 | 1.00 | GAA (0.57) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL5688782 | 1.00 | GAA (0.57) | GAAMAPTEPHX2BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL7313114 | 0.98 | GAA (0.56) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL9408124 | 0.90 | GAA (0.48) | GAAMAPT | |
| SCHEMBL27477039 | 0.85 | GAA (0.51) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL8120364 | 0.85 | GAA (0.51) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL6211215 | 0.83 | MAPT (0.46) | GAAMAPTMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL2487417 | 0.82 | GAA (0.49) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL8444853 | 0.82 | GAA (0.49) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL27604666 | 0.80 | GAA (0.46) | GAAMAPTEPHX2BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285770-B1 | PROCESS FOR THE SYNTHESIS OF ARFORMOTEROL | CIPLA LTD (IN) | 2015-05-20 | — | — | EP | claimed |
| EP-1348684-B1 | Method for synthesis of (2S)-indoline-2-carboxylic acid; and use in the synthesis of perindopril | SERVIER LAB (FR) | 2006-03-08 | — | — | EP | claimed |
| EP-0308339-B1 | PROCESS FOR THE INDUSTRIAL PREPARATION OF PERHYDROINDOLE -2(2S,3AS,7AS)-CARBOXYLIC ACID, USE IN THE PREPARATION OF CARBOXYALKYL DIPEPTIDES | ADIR ET COMPAGNIE (FR) | 1992-05-06 | — | — | EP | claimed |
| EP-0197474-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE INDOLINE-2-CARBOXYLIC ACID | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-10 | — | — | EP | claimed |
| EP-0896580-A1 | SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS | ASTA Medica Aktiengesellschaft (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997041148-A1 | SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |