Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477039 | 0.81 | GAA (0.51) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL3043496 | 0.81 | MAPT (0.45) | GAAMAPTMTNR1AMTNR1BBRD4 | |
| Hydrochloric Acid SCHEMBL3052246 | 0.80 | MAPT (0.44) | GAAMAPTMTNR1AMTNR1BBRD4 | |
| SCHEMBL1386080 | 0.80 | GAA (0.57) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL5688979 | 0.80 | GAA (0.57) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL5688782 | 0.80 | GAA (0.57) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL8444853 | 0.79 | GAA (0.49) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL2487417 | 0.79 | GAA (0.49) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| SCHEMBL8120364 | 0.78 | GAA (0.51) | GAAMAPTMTNR1AEPHX2MTNR1B | |
| Hydrochloric Acid SCHEMBL7313114 | 0.78 | GAA (0.56) | GAAMAPTMTNR1AEPHX2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100503568-C | Process for the preparation of perindopril, its analgous compounds and salts therof using 2,5 dioxo-oxazolidine intermediate compounds | ADIR (FR) | 2009-06-24 | — | — | CN | disclosed |
| CN-1529694-A | Method for preparing perindopril, analogues and salts thereof by using 2, 5-dioxo-oxazolidine intermediate compound | — | 2004-09-15 | — | — | CN | disclosed |