Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966619 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL9066655 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL11066505 | 0.90 | MEN1 (0.40) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL674004 | 0.87 | CXCR4 (0.50) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL15065334 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL15065157 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL6921848 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACHRM5CHRM3POLB | |
| SCHEMBL208440 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACHRM5CHRM3POLB | |
| SCHEMBL14006975 | 0.78 | TOP2A (0.77) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL9695349 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612448-A | POLYAMIDES WITH HIGH STRENGTH AND FLEXIBILITY | UNION CAMP CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| EP-0721473-A4 | CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS | UNION CAMP CORP (US) | 1996-09-25 | — | — | EP | claimed |
| EP-0721473-A1 | CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS | Union Camp Corporation (US) | 1996-07-17 | — | — | EP | claimed |
| EP-0442700-B1 | Two-component curable hot-melt resin compositions | UNION CAMP CORP (US) | 1996-01-03 | — | — | EP | claimed |
| WO-1995009189-A1 | CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS | UNION CAMP CORPORATION (US) | 1995-04-06 | — | — | WO | claimed |
| US-5385986-A | Improved cohesion, adhesion, ductility, flexibility; heat, solvent and moisture resistance; curable | UNION CAMP CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| EP-0441545-A1 | Two-component curable hot-melt resin compositions | Union Camp Corporation (US) | 1991-08-14 | — | — | EP | claimed |
| EP-1633743-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ | Amgen, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| EP-1631542-A1 | BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF | Amgen, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004092116-A1 | BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004092164-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-0847423-A4 | METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS | — | 1998-09-09 | — | — | EP | disclosed |
| EP-0847423-A1 | METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS | UNION CAMP CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| WO-1996041837-A1 | METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS | UNION CAMP CORPORATION (US) | 1996-12-27 | — | — | WO | disclosed |
| EP-0442700-B1 | Two-component curable hot-melt resin compositions | UNION CAMP CORP (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5424371-A | Curable blend | UNION CAMP CORPORATION (US) | 1995-06-13 | — | — | US | disclosed |
| US-5385986-A | Improved cohesion, adhesion, ductility, flexibility; heat, solvent and moisture resistance; curable | UNION CAMP CORPORATION (US) | 1995-01-31 | — | — | US | disclosed |
| US-5296557-A | Consisting of specified thermoplastic polyamide, epoxy resin | UNION CAMP CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0442700-A2 | Two-component curable hot-melt resin compositions | UNION CAMP CORPORATION (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0441545-A1 | Two-component curable hot-melt resin compositions | Union Camp Corporation (US) | 1991-08-14 | — | — | EP | disclosed |