Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689073 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBPTGS1LMNATOP2A | |
| SCHEMBL3966619 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBPTGS1LMNATOP2A | |
| SCHEMBL11066505 | 0.84 | MEN1 (0.40) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL674004 | 0.82 | CXCR4 (0.50) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL15065334 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL15065157 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGS1LMNATOP2ATOP2B | |
| SCHEMBL237512 | 0.75 | POLB (0.59) | SMN1; SMN2POLBHSD17B10CXCR4CHRM5 | |
| SCHEMBL208440 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBLMNACXCR4CHRM5 | |
| SCHEMBL6921848 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBLMNACXCR4CHRM5 | |
| SCHEMBL14006975 | 0.73 | TOP2A (0.77) | SMN1; SMN2PTGS1LMNATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442700-B1 | Two-component curable hot-melt resin compositions | UNION CAMP CORP (US) | 1996-01-03 | — | — | EP | claimed |
| EP-0442700-A2 | Two-component curable hot-melt resin compositions | UNION CAMP CORPORATION (US) | 1991-08-21 | — | — | EP | claimed |