SCHEMBL15065334

SCHEMBL15065334

CC(CN)N1CCN(CC(C)N2CCNCC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
PTGS1 P23219 2/20 0.36
LMNA P02545 1/20 0.36
TOP2A P11388 1/20 0.36
TOP2B Q02880 1/20 0.36
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10305702 0.87 MEN1 (0.33) SMN1; SMN2CHRM5CHRM3
SCHEMBL5689073 0.85 SMN1; SMN2 (0.46) SMN1; SMN2PTGS1LMNATOP2ATOP2B
SCHEMBL3966619 0.83 SMN1; SMN2 (0.44) SMN1; SMN2PTGS1LMNATOP2ATOP2B
SCHEMBL15065157 0.82 SMN1; SMN2 (0.42) SMN1; SMN2PTGS1LMNATOP2ATOP2B
SCHEMBL9066655 0.79 SMN1; SMN2 (0.42) SMN1; SMN2PTGS1LMNATOP2ATOP2B
SCHEMBL11066505 0.79 MEN1 (0.40) SMN1; SMN2PTGS1LMNATOP2ATOP2B
SCHEMBL9695349 0.78
SCHEMBL11224155 0.76 ALDH1A1 (0.37)
SCHEMBL21096753 0.76
SCHEMBL674004 0.74 CXCR4 (0.50) SMN1; SMN2PTGS1LMNATOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9688875-B2 Epoxy coating systems using polycyclic polyamines as epoxy hardeners DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-27 US claimed
EP-2797981-B1 EPOXY COATING SYSTEMS USING POLYCYCLIC POLYAMINES AS EPOXY HARDENERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-24 EP claimed
EP-2797901-B1 FORMATION OF HIGHER MOLECULAR WEIGHT CYCLIC POLYAMINE COMPOUNDS FROM CYCLIC POLYAMINE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-10 EP claimed
US-9162995-B2 Formation of higher molecular weight cyclic polyamine compounds from cyclic polyamine compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-20 US claimed
US-20150011762-A1 FORMATION OF HIGHER MOLECULAR WEIGHT CYCLIC POLYAMINE COMPOUNDS FROM CYCLIC POLYAMINE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC 2015-01-08 US claimed
EP-2797981-A1 EPOXY COATING SYSTEMS USING POLYCYCLIC POLYAMINES AS EPOXY HARDENERS Dow Global Technologies LLC (US) 2014-11-05 EP claimed
WO-2013102006-A1 EPOXY COATING SYSTEMS USING POLYCYCLIC POLYAMINES AS EPOXY HARDENERS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO claimed
US-9908966-B2 Adduct curing agents DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-06 US disclosed
US-9822324-B2 Amine alkoxylate compositions and their use as lubricant additives DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-21 US disclosed
US-9688875-B2 Epoxy coating systems using polycyclic polyamines as epoxy hardeners DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-27 US disclosed
EP-2797981-B1 EPOXY COATING SYSTEMS USING POLYCYCLIC POLYAMINES AS EPOXY HARDENERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-24 EP disclosed
US-9656977-B2 Polyamide hardeners for epdxy resins DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-23 US disclosed
EP-2797903-B1 AMINE POLYETHER POLYOLS AND POLYURETHANE FOAM COMPOSITIONS MADE FROM CYCLIC AMINE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-17 EP disclosed
WO-2014066088-A1 AMINE ALKOXYLATE COMPOSITIONS AND THEIR USE AS LUBRICANT ADDITIVES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-01 WO disclosed
WO-2014066386-A1 POLYAMIDE HARDENERS FOR EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-01 WO disclosed
WO-2014066450-A2 WEATHERABLE COATINGS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-01 WO disclosed
WO-2013102097-A2 CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013101345-A1 FORMATION OF HIGHER MOLECULAR WEIGHT CYCLIC POLYAMINE COMPOUNDS FROM CYCLIC POLYAMINE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013102053-A1 AMINE POLYETHER POLYOLS AND POLYURETHANE FOAM COMPOSITIONS MADE FROM CYCLIC AMINE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013102006-A1 EPOXY COATING SYSTEMS USING POLYCYCLIC POLYAMINES AS EPOXY HARDENERS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011762-A1 FORMATION OF HIGHER MOLECULAR WEIGHT CYCLIC POLYAMINE COMPOUNDS FROM CYCLIC POLYAMINE COMPOUNDS SRM, PCNA, SMS SMN1; SMN2 4450/4885PTGS1 2122/4885LMNA 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.