Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975809 | 0.79 | — | — | |
| SCHEMBL9938062 | 0.77 | LMNA (0.52) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL4282650 | 0.77 | SLC6A2 (0.41) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Sorbitol SCHEMBL5050896 | 0.73 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL22075548 | 0.73 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL16153889 | 0.72 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL14411837 | 0.72 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL16153910 | 0.72 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9258595 | 0.72 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL15476270 | 0.72 | TDP1 (0.63) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637038-A2 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2006-03-22 | — | — | EP | disclosed |
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AIR PRODUCTS AND CHEMICALS, INC. | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AGL, SFN, MGAT1 | LMNA 492/4885L3MBTL1 2608/4885TDP1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.