Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5689489 | 0.94 | CTSS (0.31) | — | |
| Hydrochloric Acid SCHEMBL4475684 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL4468996 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL4465283 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4479685 | 0.85 | PSMB5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5691364 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL4465722 | 0.84 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4478037 | 0.83 | HSD11B1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4463321 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL4462941 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511755-B1 | TRANSITION METAL COMPOUNDS THEIR PREPARATION AND THEIR USE IN CATALYST SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| US-20050182266-A1 | Transition metal componds their preparation and their use in catalyst systems for the polymerization and copolymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-08-18 | — | — | US | disclosed |