Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401546 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNATP53RAB9AMAPT | |
| SCHEMBL3167627 | 0.84 | LTA4H (0.50) | ALDH1A1LMNATP53RAB9AMAPT | |
| SCHEMBL3732372 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL305162 | 0.82 | MAPT (0.68) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL26023562 | 0.82 | MAPT (0.68) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL20022995 | 0.82 | TSHR (0.58) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL16320886 | 0.81 | PLA2G4B (0.58) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3727515 | 0.80 | FFAR1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16672454 | 0.80 | TDP1 (0.56) | ALDH1A1LMNANPC1SMN1; SMN2TSHR | |
| SCHEMBL31329294 | 0.80 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |