Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672454 | 0.92 | TDP1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL3167627 | 0.89 | LTA4H (0.50) | ALDH1A1MAPK1L3MBTL1TDP1POLB | |
| SCHEMBL5689482 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRPOLBTP53MEN1 | |
| SCHEMBL20022968 | 0.83 | TSHR (0.53) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL1177836 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1POLB | |
| SCHEMBL1396777 | 0.82 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1TDP1TSHRRECQL | |
| SCHEMBL1855116 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL17084551 | 0.82 | TDP1 (0.67) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL8681578 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1POLB | |
| SCHEMBL30610377 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55133304-A | — | — | None | — | — | JP | disclosed |
| EP-2869389-B1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME | MITSUBISHI CHEM CORP (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-10320030-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-06-11 | — | — | US | disclosed |
| US-20180022853-A1 | METHOD FOR PRODUCING AN ABLATIVE RESIN | ARIANEGROUP SAS (FR) | 2018-01-25 | — | — | US | disclosed |
| US-20180009928-A1 | METHOD FOR PRODUCING AN ABLATIVE RESIN | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-01-11 | — | — | US | disclosed |
| CN-107531653-A | Novel difluoroketoamide derivatives | 豪夫迈·罗氏有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107207421-A | New trifluoromethyl propanamide derivative | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20150140448-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2869389-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME | Mitsubishi Chemical Corporation (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| JP-S55133304-A | PERFUME CONTROLLER | SHISEIDO CO LTD | 1980-10-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | ALDH1A1 1423/4885MAPK1 4216/4885L3MBTL1 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.