SCHEMBL5690099

SCHEMBL5690099

CCCCCCCCCCCCCCCCCC(=O)OCC(CNC(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
PRKCA P17252 4/20 0.59
PRKCE Q02156 2/20 0.59
PRKCQ Q04759 2/20 0.59
PRKCD Q05655 2/20 0.59
LPAR3 Q9UBY5 7/20 0.53
LPAR1 Q92633 4/20 0.53
ENPP2 Q13822 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
LPAR2 Q9HBW0 2/20 0.52
TLR2 O60603 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5689676 1.00 ALDH1A1 (0.63) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL30085025 1.00 ALDH1A1 (0.63) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL5690133 1.00 ALDH1A1 (0.63) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18072622 0.93 PRKCA (0.64) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL27167195 0.89 ALDH1A1 (0.66) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL27167196 0.89 ALDH1A1 (0.66) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL7755332 0.87 PRKCA (0.59) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL7755337 0.87 PRKCA (0.59) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL14452769 0.87 ALDH1A1 (0.70) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL29040598 0.86 ALDH1A1 (0.68) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041976-B1 POLYAMIDE OLIGOMERS INEX PHARMACEUTICALS CORP (CA) 2006-04-05 EP disclosed
US-6586559-B2 Based on omega-amino (oligoethyleneglycol) alkanoic acid monomers; can be conjugated to lipids, nucleic acids, peptides, proteins, etc and used to form liposomes, virusomes, micelles, etc., optionally containing drugs INEX PHARMACEUTICALS CORPORATION (CA) 2003-07-01 US disclosed
US-20020026027-A1 Polyamide oligomers TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2002-02-28 US disclosed
US-6320017-B1 POLYLACTONES FROM OMEGA-AMINO(OLIGOETHYLENE OXIDE)ALKANOIC ACID MONOMERS; CAN BE CONJUGATED TO LIPIDS, NUCLEIC ACIDS, PEPTIDES, PROTEINS, ETC. INEX PHARMACEUTICALS CORP. (CA) 2001-11-20 US disclosed
EP-1041976-A1 POLYAMIDE OLIGOMERS Inex Pharmaceuticals Corp. (CA) 2000-10-11 EP disclosed
WO-1999033493-A1 POLYAMIDE OLIGOMERS INEX PHARMACEUTICALS CORPORATION (CA) 1999-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020026027-A1 Polyamide oligomers CLTA, PICALM, PUF60 ALDH1A1 4835/4885LMNA 1198/4885PRKCA 3744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.