Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870317 | 0.77 | MAPT (0.49) | MAPTATMALDH1A1PDE1CHPGD | |
| SCHEMBL10993468 | 0.67 | CNR2 (0.47) | CFTRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12826413 | 0.66 | TSHR (0.54) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4870467 | 0.66 | SLC6A4 (0.46) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5688033 | 0.66 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5435679 | 0.66 | PGR (0.58) | CFTRMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL28712258 | 0.65 | MEN1 (0.44) | MAPTATMALDH1A1PDE1CMEN1 | |
| Dinitrophenylene SCHEMBL28012196 | 0.63 | TSHR (0.63) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29526232 | 0.63 | TSHR (0.67) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2009026 | 0.63 | TSHR (0.67) | MAPTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635827-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110442-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-12-23 | — | — | WO | disclosed |