Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5687416 | 0.82 | HRH2 (0.38) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11170232 | 0.77 | TDP1 (0.59) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10992087 | 0.76 | CDC7 (0.50) | MAPTALDH1A1MMP2MMP9MMP8 | |
| SCHEMBL10996778 | 0.68 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7534057 | 0.67 | MEN1 (0.51) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL30770331 | 0.67 | MAPT (0.74) | MAPTALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5690136 | 0.66 | CFTR (0.43) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3389458 | 0.66 | KMT2A (0.57) | MAPTALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9650830 | 0.65 | NPC1 (0.54) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL5072717 | 0.65 | TSHR (0.68) | MAPTALDH1A1SLC6A3TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635827-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110442-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-12-23 | — | — | WO | disclosed |