Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | YWHAG | P61981 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245747 | 0.90 | ALDH1A1 (0.66) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL8180121 | 0.86 | ALDH1A1 (0.61) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL3396096 | 0.86 | LMNA (0.66) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| Phenylbutanoic Acid SCHEMBL31386998 | 0.86 | MAPK1 (0.66) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL1434644 | 0.84 | ALDH1A1 (0.73) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL6025448 | 0.83 | TDP1 (0.66) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL8566030 | 0.83 | ALDH1A1 (0.66) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL419309 | 0.82 | ESR1 (0.64) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| Phenethyl Propionate SCHEMBL28250149 | 0.82 | ALOX5 (0.61) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL7290583 | 0.81 | TDP1 (0.75) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |