Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547877 | 0.92 | L3MBTL1 (0.51) | HTTL3MBTL1GAAPOLBFFAR1 | |
| SCHEMBL6548648 | 0.89 | L3MBTL1 (0.55) | HTTL3MBTL1GAAPOLBAPEX1 | |
| SCHEMBL6549409 | 0.88 | GAA (0.56) | HTTL3MBTL1GAAPLA2G4BPOLB | |
| SCHEMBL8894826 | 0.88 | PLA2G4B (0.46) | HTTL3MBTL1PLA2G4BPOLBAPEX1 | |
| SCHEMBL6547959 | 0.88 | HTT (0.49) | HTTL3MBTL1GAAPOLBMAPT | |
| SCHEMBL3963156 | 0.88 | HTT (0.43) | HTTL3MBTL1GAAPLA2G4BPOLB | |
| SCHEMBL3963155 | 0.88 | HTT (0.43) | HTTL3MBTL1GAAPLA2G4BPOLB | |
| SCHEMBL6549825 | 0.87 | HTT (0.43) | HTTL3MBTL1GAAPLA2G4BMAPT | |
| SCHEMBL8660004 | 0.87 | MAPT (0.51) | HTTL3MBTL1GAAPOLBTDP1 | |
| SCHEMBL13606721 | 0.86 | HTT (0.41) | HTTL3MBTL1GAAPLA2G4BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638924-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | Syngenta Participations AG (CH) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113273-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-12-29 | — | — | WO | disclosed |