Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894549 | 0.98 | TP53 (0.47) | PLA2G4BALDH1A1L3MBTL1PKMPLAU | |
| SCHEMBL8897462 | 0.96 | TP53 (0.49) | PLA2G4BALDH1A1L3MBTL1PKMPLAU | |
| SCHEMBL6547658 | 0.90 | PPARA (0.48) | ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL8895438 | 0.89 | PLA2G4B (0.45) | PLA2G4BALDH1A1L3MBTL1PKMPLAU | |
| SCHEMBL6547877 | 0.89 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1HTTPOLB | |
| SCHEMBL5690281 | 0.88 | HTT (0.47) | PLA2G4BL3MBTL1PLAUTP53TSHR | |
| SCHEMBL6549825 | 0.87 | HTT (0.43) | PLA2G4BALDH1A1L3MBTL1HTT | |
| SCHEMBL8022439 | 0.87 | PPARA (0.51) | ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL8895257 | 0.87 | KMT2A (0.49) | PLA2G4BPLAUNR4A2POLB | |
| SCHEMBL8660004 | 0.87 | MAPT (0.51) | ALDH1A1L3MBTL1HTTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | claimed |
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |