SCHEMBL5690458

SCHEMBL5690458

O=C(O)[C@@H]1CCCN1C(=O)OCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PREP P48147 3/20 0.44
RAB9A P51151 1/20 0.44
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
GFER P55789 1/20 0.42
GYS1 P13807 1/20 0.42
CTRB1 P17538 1/20 0.42
TSHR P16473 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
UCHL1 P09936 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30762653 1.00 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
SCHEMBL29074159 0.96 PREP (0.48) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
SCHEMBL28510227 0.96 PREP (0.48) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
SCHEMBL7112033 0.94 PNMT (0.42) ALDH1A1SMN1; SMN2PREPRAB9A
SCHEMBL7112036 0.94 PNMT (0.42) ALDH1A1SMN1; SMN2PREPRAB9A
Cysteine SCHEMBL28072401 0.90 CTRB1 (0.43) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
SCHEMBL6499664 0.87 PNMT (0.38) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
Asparagine SCHEMBL28525733 0.86 KMT2A (0.38) ALDH1A1SMN1; SMN2PREPRAB9ACHRM2
SCHEMBL7096634 0.85 CHRM2 (0.43) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL28885251 0.85 CD274 (0.41) PREPNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 CN claimed
WO-2024017317-A1 HER2 TARGETING PEPTIDE MOLECULE AND USE THEREOF 中国科学院上海药物研究所 2024-01-25 WO claimed
CN-117430670-A HER2 targeting peptide molecule and application thereof 中国科学院上海药物研究所 2024-01-23 CN claimed
CN-115744879-A Carbon quantum dot solution, temperature-sensitive material, preparation method and application 河北科技大学 2023-03-07 CN claimed
CN-108484735-B Synthesis method of wide-activity cyclic heptapeptide Reniochalistatin A-D 暨南大学 2020-12-15 CN claimed
CN-106674230-B The synthetic method of pro-his cyclic dipeptide 陕西慧康生物科技有限责任公司 2019-07-02 CN claimed
CN-108586307-A A kind of preparation method of anhydrous fluorenylmethyloxycarbonyl-L-PROLINE 成都市科隆化学品有限公司 2018-09-28 CN claimed
CN-108373496-A Inoxidizability polypeptide GTMGAVGPRG and preparation method thereof 安徽工程大学 2018-08-07 CN claimed
CN-106674230-A Synthesis method of histidine and proline cyclodipeptide 陕西慧康生物科技有限责任公司 2017-05-17 CN claimed
CN-105777866-A Anti-hypertension bioactive peptide and preparing method thereof 南京大学 2016-07-20 CN claimed
CN-122075733-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 2026-05-26 CN disclosed
CN-122031713-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 乐普生物科技股份有限公司 2026-05-15 CN disclosed
CN-121537485-A Cyclohexapeptide and preparation method and application thereof 未来多肽生物科技(烟台)有限公司 2026-02-17 CN disclosed
EP-4659764-A1 LINKER DRUG, AND PREPARATION METHOD AND USE OF ANTIBODY-DRUG CONJUGATE THEREOF Lepu Biopharma Co., Ltd. (CN) 2025-12-10 EP disclosed
EP-4610271-A1 SELF-ASSEMBLING POLYPEPTIDE AND USE THEREOF Sucess Bio-Tech Co., Ltd. (CN) 2025-09-03 EP disclosed
US-20040053844-A1 Peptide and osteogenetic accelerator KYOCERA CORPORATION 2004-03-18 US disclosed
US-6617307-B1 Useful for treatment of fractures, as a filler in deficient sites of bone, for inhibition of decrease in bone substance related to osteoporosis and periodontic diseases KYOCERA CORPORATION (JP) 2003-09-09 US disclosed
US-20030082784-A1 Novel peptide having osteogenetic activity and osteogenetic accelerator containing the same YOSHIHIKO NISHIMURA 2003-05-01 US disclosed
EP-1288228-A1 BMP-2-derived peptides having osteogenetic activity and osteogenetic accelerator containing the same Nishimura, Yoshihiko (JP) 2003-03-05 EP disclosed
EP-1006126-A2 Osteogenic peptides Nishimura, Yoshihiko (JP) 2000-06-07 EP disclosed