Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106783 | 0.84 | ALDH1A1 (0.55) | PTPRCPTPN1XDHRAB9ALMNA | |
| SCHEMBL30136447 | 0.84 | ALDH1A1 (0.58) | PTPRCPTPN1XDHRAB9ALMNA | |
| SCHEMBL294721 | 0.84 | ALDH1A1 (0.58) | PTPRCPTPN1XDHRAB9ALMNA | |
| SCHEMBL14264233 | 0.83 | PTPRC (0.50) | SQORPTPRCPTPN1RAB9ALMNA | |
| SCHEMBL17535975 | 0.83 | ERN1 (0.51) | SQORSLC6A4SLC6A3APPCA12 | |
| SCHEMBL1704521 | 0.83 | ABL1 (0.62) | PTPRCPTPN1XDHAPPCA12 | |
| SCHEMBL4425113 | 0.83 | SYK (0.56) | PTPRCPTPN1XDHRAB9ALMNA | |
| SCHEMBL1680715 | 0.82 | ALDH1A1 (0.52) | PTPRCPTPN1XDHRAB9ALMNA | |
| Biphenyl SCHEMBL9989359 | 0.82 | ALDH1A1 (0.56) | PTPRCPTPN1XDHRAB9ALMNA | |
| SCHEMBL17599648 | 0.82 | SLC6A4 (0.47) | SQORSLC6A4SLC6A3XDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57098228-A | — | — | None | — | — | JP | disclosed |
| CN-103044477-B | Trimethyl silicane replaces benzopyrans compounds and application thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-05 | — | — | CN | disclosed |
| WO-2013139341-A1 | GPR120 RECEPTOR MODULATORS | SYDDANSK UNIVERSITET (DK) | 2013-09-26 | — | — | WO | disclosed |
| CN-103044477-A | Trimethyl silicon substituted benzopyran compound and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-04-17 | — | — | CN | disclosed |
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| JP-S5798228-A | BIPHENYL DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1982-06-18 | — | — | JP | disclosed |