Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106783 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| SCHEMBL294721 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| SCHEMBL30136447 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| Biphenyl SCHEMBL9989359 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| SCHEMBL30017788 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| Methyl Alcohol SCHEMBL28372647 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| Methylamine SCHEMBL28363123 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| SCHEMBL20550260 | 0.87 | PTPRC (0.54) | ALDH1A1KDM4ELMNAGAAPTPRC | |
| SCHEMBL12326181 | 0.86 | MAOA (0.53) | ALDH1A1KDM4EPTPRCPTPN1MEN1 | |
| SCHEMBL27755757 | 0.86 | SYK (0.56) | ALDH1A1KDM4ELMNAGAAPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837973-A | Fragrance materials | PROCTER & GAMBLE | 2015-08-12 | — | — | CN | disclosed |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | NAKAMOTO KAZUTAKA | 2011-08-11 | — | — | US | disclosed |
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-7829585-B2 | Antifungal agent containing pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1864980-A1 | ANTIFUNGAL AGENT CONTAINING PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | ALDH1A1 112/4885KDM4E 1550/4885LMNA 4075/4885 |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | ERG28, CYP51A1, XPO1 | ALDH1A1 1677/4885KDM4E 3112/4885LMNA 2372/4885 |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | ALDH1A1 1459/4885KDM4E 3245/4885LMNA 2208/4885 |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | ERG28, SQOR, CYP51A1 | ALDH1A1 602/4885KDM4E 2090/4885LMNA 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.