Biphenyl

Biphenyl

SCHEMBL9989359

COc1ccccc1-c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 2/20 0.56
LMNA P02545 2/20 0.56
GAA P10253 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
APP P05067 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
TP53 P04637 2/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PTPRC P08575 1/20 0.52
PTPN1 P18031 1/20 0.52
HTR7 P34969 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24106783 0.98 ALDH1A1 (0.55) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL294721 0.98 ALDH1A1 (0.58) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL30136447 0.98 ALDH1A1 (0.58) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL30017788 0.95 ALDH1A1 (0.56) ALDH1A1KDM4ELMNAGAACA12
Methylamine SCHEMBL28363123 0.93 ALDH1A1 (0.55) ALDH1A1KDM4ELMNAGAACA12
Methyl Alcohol SCHEMBL28372647 0.93 ALDH1A1 (0.55) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL1680715 0.91 ALDH1A1 (0.52) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL27755757 0.90 SYK (0.56) ALDH1A1KDM4ELMNAGAASMN1; SMN2
SCHEMBL28102075 0.89 HTR7 (0.51) ALDH1A1KDM4ELMNAGAACA12
SCHEMBL28043787 0.89 HTR7 (0.51) ALDH1A1KDM4ELMNAGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110308790-A1 IN SITU METHANOGENESIS MODELING AND RISK ANALYSIS CONOCOPHILLIPS COMPANY (US) 2011-12-22 US disclosed
US-4723963-A CONTAINING OXYGENATED AROMATIC COMPOUNDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1988-02-09 US disclosed