SCHEMBL5690806

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5690023	0.90	TMEM97 (0.60)	TMEM97SIGMAR1GFERNPC1RAB9A
	SCHEMBL5450120	0.89	TMEM97 (0.57)	TMEM97SIGMAR1NPBWR1MCHR1NPC1
	SCHEMBL5689952	0.89	CXCR3 (0.57)	TMEM97SIGMAR1NPBWR1MCHR1CXCR3
	SCHEMBL5690246	0.89	TMEM97 (0.56)	TMEM97SIGMAR1NPC1RAB9ACXCR3
	SCHEMBL5861658	0.87	MAPT (0.60)	TMEM97SIGMAR1GFERNPC1RAB9A
	SCHEMBL5690040	0.85	ERCC1 (0.58)	TMEM97SIGMAR1NPBWR1MCHR1CXCR3
	SCHEMBL5690320	0.84	ENPP2 (0.57)	TMEM97SIGMAR1RAB9ACXCR3MEN1
	SCHEMBL5861502	0.84	TMEM97 (0.58)	TMEM97SIGMAR1RAB9ACXCR3KMT2A
	SCHEMBL5690532	0.83	TMEM97 (0.56)	TMEM97SIGMAR1CXCR3MEN1KMT2A
	SCHEMBL5860142	0.82	CXCR3 (0.60)	TMEM97SIGMAR1CXCR3ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.