SCHEMBL5690948

SCHEMBL5690948

C=C(c1ccccc1)c1ccc(N)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
PIK3CA P42336 1/20 0.37
POLB P06746 2/20 0.36
MAPT P10636 4/20 0.36
GAA P10253 1/20 0.36
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPK14 Q16539 1/20 0.34
RXRA P19793 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP26A1 O43174 1/20 0.33
ABCB11 O95342 1/20 0.33
ESR1 P03372 1/20 0.33
PGR P06401 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10601803 0.81 MEN1 (0.41) KMT2AMEN1CYP3A4TSHRMAPT
SCHEMBL10692941 0.80 GAA (0.42) CYP3A4MAPTGAAALDH1A1SMN1; SMN2
SCHEMBL4456996 0.78 MAPT (0.58) KMT2AMEN1TSHRPOLBMAPT
SCHEMBL29726796 0.76 MAPT (0.49) KMT2AMEN1CYP3A4POLBMAPT
SCHEMBL10696057 0.76 PARP10 (0.45) KMT2AMEN1TSHRPOLBMAPT
Hydrochloric Acid SCHEMBL9391090 0.75 CES2 (0.48) POLBMAPTGAALMNAALDH1A1
SCHEMBL6299937 0.74 MAPT (0.57) KMT2AMEN1CYP3A4TSHRPOLB
SCHEMBL29593727 0.74 MAPT (0.57) KMT2AMEN1CYP3A4TSHRPOLB
SCHEMBL6546288 0.73 KMT2A (0.42) KMT2AMEN1CYP3A4TSHRPOLB
SCHEMBL22708268 0.72 MEN1 (0.40) KMT2AMEN1POLBMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1059164-B1 Image recording material and planographic printing plate using same FUJI PHOTO FILM CO LTD (JP) 2006-04-19 EP disclosed
US-6383714-B1 COMPOUNDS DECOMPOSABLE BY LIGHT AND HEAT, CROSSLINKING, INFRARED ABSORBERS FUJI PHOTO FILM CO., LTD. (JP) 2002-05-07 US disclosed
EP-1059164-A2 Image recording material and planographic printing plate using same FUJI PHOTO FILM CO., LTD. (JP) 2000-12-13 EP disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed