SCHEMBL10692941

SCHEMBL10692941

C=C(c1ccc(OC)cc1)c1ccc(N)c(C)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
PARP10 Q53GL7 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
PARP1 P09874 1/20 0.41
PARP2 Q9UGN5 1/20 0.41
PARP4 Q9UKK3 1/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP3A4 P08684 2/20 0.37
HDAC3 O15379 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10696057 0.83 PARP10 (0.45) MAPTPARP10PRSS1PRSS2PRSS3
SCHEMBL5690948 0.80 KMT2A (0.39) GAAMAPTALDH1A1CYP3A4SMN1; SMN2
SCHEMBL11822666 0.79 CES2 (0.59) GAAMAPTCA1CA2PARP10
SCHEMBL3277627 0.74 MAPT (0.59) MAPTCA1CA2PARP10PRSS1
SCHEMBL5961802 0.71 NQO1 (0.50) GAAMAPTPARP10PRSS1PRSS2
SCHEMBL14264170 0.71 ACHE (0.65) MAPTCA1CA2PARP10PRSS1
SCHEMBL29726801 0.71 NOS2 (0.52) GAAMAPTCES2CES1TDP1
SCHEMBL10679674 0.69 PARP10 (0.59) MAPTCA1CA2PARP10PRSS1
SCHEMBL15232917 0.69 PDE4A (0.56) MAPTCA1CA2PARP10PRSS1
SCHEMBL9822803 0.69 MEN1 (0.49) GAAMAPTMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed