Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657326 | 0.81 | HDAC2 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10801036 | 0.80 | FOLH1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11544593 | 0.80 | FOLH1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14279160 | 0.79 | NAAA (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11576579 | 0.79 | FOLH1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14279162 | 0.78 | L3MBTL1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12045762 | 0.78 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11545905 | 0.77 | NAAA (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10801725 | 0.76 | FOLH1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8975695 | 0.76 | FOLH1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268505-B1 | SOLID PHASE SYNTHESIS METHOD AND REAGENT | SURMODICS INC (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-0888389-B1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1268505-A2 | SOLID PHASE SYNTHESIS METHOD AND REAGENT | SurModics, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6410643-B1 | COUPLING NUCLEOTIDE TO SUPPORT | SURMODICS, INC. | 2002-06-25 | — | — | US | disclosed |
| WO-2001066554-A2 | SOLID PHASE SYNTHESIS METHOD AND REAGENT | SURMODICS, INC. (US) | 2001-09-13 | — | — | WO | disclosed |
| EP-0888389-A4 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5942555-A | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom | SURMODICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0888389-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SurModics, Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034935-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | BSI CORPORATION (US) | 1997-09-25 | — | — | WO | disclosed |