Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057040 | 0.84 | HDAC3 (0.37) | HDAC3CHRM1SMN1; SMN2HSD17B3 | |
| SCHEMBL29493251 | 0.83 | HDAC3 (0.41) | NPSR1HDAC3ALDH1A1TSHRMAPK1 | |
| SCHEMBL15056964 | 0.83 | HDAC3 (0.41) | NPSR1HDAC3ALDH1A1TSHRMAPK1 | |
| SCHEMBL324299 | 0.80 | P2RX4 (0.52) | NPSR1ALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL5721697 | 0.80 | ALDH1A1 (0.41) | CYP3A4HDAC3ALDH1A1TSHRMAPK1 | |
| SCHEMBL15056629 | 0.79 | HDAC3 (0.39) | HDAC3ALDH1A1HSD17B3 | |
| SCHEMBL325210 | 0.78 | HDAC3 (0.38) | HDAC3MAPK1MEN1KMT2AHSD17B3 | |
| SCHEMBL324590 | 0.78 | HDAC3 (0.38) | HDAC3HSD17B3 | |
| SCHEMBL28245916 | 0.78 | NPC1 (0.42) | NPSR1HDAC3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL324125 | 0.78 | P2RX4 (0.53) | HDAC3ALDH1A1TSHRCHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263924-B | Cxcr7 receptor modulators | 爱杜西亚制药有限公司 | 2018-10-19 | — | — | CN | disclosed |
| EP-1660439-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Transtech Pharma, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014533-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |