Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | LPO | P22079 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692504 | 0.82 | CYP2C19 (0.68) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL3072588 | 0.80 | CYP2C19 (0.67) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL29394966 | 0.77 | ALDH1A1 (1.00) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL431534 | 0.77 | ALDH1A1 (1.00) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL20865 | 0.77 | ALDH1A1 (1.00) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL12872719 | 0.76 | CYP1A2 (0.68) | CYP2C19ALDH1A1LMNABAZ2BSMN1; SMN2 | |
| Orotic Acid SCHEMBL23859825 | 0.76 | ALDH1A1 (0.95) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL122311 | 0.76 | ALDH1A1 (0.95) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL896844 | 0.76 | ALDH1A1 (0.95) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 | |
| Orotic Acid SCHEMBL1005001 | 0.76 | ALDH1A1 (0.95) | CYP2C19ALDH1A1LMNASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452387-B | Polysiloxane capable of being cured by ultraviolet light and preparation method and application thereof | 广东工业大学 | 2021-06-15 | — | — | CN | disclosed |
| EP-1644338-A1 | 2, 4, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | Aponetics AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004087679-A1 | 2, 4, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | APONETICS AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-4113950-A | PROCESS FOR PREPARING OROTIC ACID AND THIOOROTIC ACID | DIAMALT AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4062847-A | Process for preparing orotic acid | DIAMALT AKTIENGESELLSCHAFT (DT) | 1977-12-13 | — | — | US | disclosed |