Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805590 | 0.73 | LMNA (0.36) | POLBALDH1A1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL812692 | 0.70 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5692832 | 0.70 | CA1 (0.48) | CA1CA2TSHRGAAALDH1A1 | |
| SCHEMBL5391581 | 0.67 | MEN1 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3620944 | 0.66 | GAA (0.53) | CA1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL8113065 | 0.65 | TSHR (0.66) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL813077 | 0.65 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL16295123 | 0.64 | CA1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL812919 | 0.64 | TSHR (0.70) | CA1CA2TSHRGAAPOLB | |
| SCHEMBL4281632 | 0.64 | ALDH1A1 (0.54) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638553-A1 | NEW USE I | BIOVITRUM AB (SE) | 2006-03-29 | — | — | EP | claimed |
| WO-2004112784-A1 | NEW USE I | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | claimed |