SCHEMBL812919

SCHEMBL812919

Cc1cc(C)c(S(=O)(=O)Nc2ccccc2)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
GAA P10253 3/20 0.70
POLB P06746 1/20 0.70
GFER P55789 1/20 0.70
ALDH1A1 P00352 2/20 0.67
LMNA P02545 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
HTT P42858 1/20 0.65
MAPT P10636 4/20 0.64
RAB9A P51151 1/20 0.64
CYP1A2 P05177 2/20 0.63
CYP3A4 P08684 2/20 0.63
CYP2C19 P33261 2/20 0.63
MAPK1 P28482 1/20 0.63
MCOLN3 Q8TDD5 1/20 0.62
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31405467 0.86 LMNA (0.70) TSHRGAAPOLBGFERALDH1A1
SCHEMBL10246054 0.83 ALDH1A1 (0.68) TSHRGAAPOLBGFERALDH1A1
SCHEMBL5960099 0.82 GAA (1.00) TSHRGAAPOLBGFERALDH1A1
SCHEMBL29118845 0.82 GAA (0.71) TSHRGAAPOLBGFERALDH1A1
SCHEMBL94670 0.82 GAA (0.71) TSHRGAAPOLBGFERALDH1A1
SCHEMBL8113065 0.82 TSHR (0.66) TSHRGAAPOLBGFERALDH1A1
SCHEMBL22124696 0.82 IDH1 (0.58) TSHRGAAPOLBGFERALDH1A1
SCHEMBL25749442 0.81 LMNA (0.70) TSHRGAAPOLBGFERALDH1A1
SCHEMBL15761581 0.81 IDH1 (0.53) TSHRGAAPOLBGFERALDH1A1
SCHEMBL3363956 0.80 ALDH1A1 (0.57) TSHRGAAPOLBGFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109851548-B Preparation method of 2, 3-disubstituted indole compound 大连理工大学 2022-05-17 CN disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 US disclosed
US-9091804-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2015-07-28 US disclosed
US-8632863-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-01-21 US disclosed
US-20130253182-A1 POLYMER FILM, AND OPTICALLY-COMPENSATORY FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE COMPRISING THE SAME NISHIURA TAKAKO (JP) 2013-09-26 US disclosed
US-20130222720-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE KONICA MINOLTA , INC. (JP) 2013-08-29 US disclosed
US-8445081-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2013-05-21 US disclosed
CN-102007185-B Gas barrier composition, coating film, method for producing the gas barrier composition, method for producing the coating film, and multilayer body MITSUI CHEMICALS INC 2013-04-24 CN disclosed
US-20090202823-A1 Cellulose Ester Film, Polarizing Plate and Display MURAKAMI TAKASHI 2009-08-13 US disclosed
US-20080254237-A1 Polymer Film, and Optically-Compensatory Film, Polarizer and Liquid-Crystal Display Device Comprising the Same FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080138541-A1 Optical Film, Method for Producing Optical Film, Optically-Compensatory Film, Polarizing Plate and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
CN-101171297-A Gas barrier composition, coating film, methods for producing those, and multilayer body MITSUI CHEMICALS INC (JP) 2008-04-30 CN disclosed
US-20080084523-A1 LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-04-10 US disclosed
US-20080049324-A1 Polarizing plate protective film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2008-02-28 US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 US disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed