Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756302 | 0.76 | LMNA (0.41) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL217367 | 0.71 | LMNA (0.38) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3769766 | 0.70 | MEN1 (0.55) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10435815 | 0.69 | SETD7 (0.37) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5077508 | 0.67 | LMNA (0.34) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL34469386 | 0.67 | LMNA (0.46) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1161991 | 0.67 | LMNA (0.46) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5921807 | 0.66 | LMNA (0.50) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9617411 | 0.66 | LMNA (0.50) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4599054 | 0.65 | LMNA (0.44) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975644-B1 | SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM | BOREALIS TECH OY (FI) | 2005-03-16 | — | — | EP | claimed |
| EP-1448633-B2 | TWO-STEP POLYMERIZATION PROCESS | BOREALIS TECH OY (FI) | 2012-06-13 | — | — | EP | disclosed |
| EP-1448633-B1 | TWO-STEP POLYMERIZATION PROCESS | BOREALIS TECH OY (FI) | 2006-04-26 | — | — | EP | disclosed |
| CN-1247603-C | Substituted metallocene compounds for olefin polymerization catalyst systems, their intermediates and methods for preparing them | BOREALIS AS (DK) | 2006-03-29 | — | — | CN | disclosed |
| EP-1448633-A1 | TWO-STEP POLYMERIZATION PROCESS | Borealis Technology Oy (FI) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003037941-A1 | TWO-STEP POLYMERIZATION PROCESS | BOREALIS TECHNOLOGY OY (FI) | 2003-05-08 | — | — | WO | disclosed |
| US-6355819-B1 | TRANSITION METAL METALLOCENES WITH HETEROATOM 1- OR 3-SUBSTITUTED INDENYL AND INDENYL DERIVATIVE LIGANDS | BOREALIS TECHNOLOGY OY (FI) | 2002-03-12 | — | — | US | disclosed |
| CN-1255139-A | Substituted metallocene compounds for olefin polymerization catalyst systems, their intermediates and methods for preparing them | BOREALIS AS (DK) | 2000-05-31 | — | — | CN | disclosed |
| EP-0975644-A1 | SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM | BOREALIS A/S (DK) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046616-A1 | SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM | BOREALIS A/S (DK) | 1998-10-22 | — | — | WO | disclosed |