SCHEMBL756302

SCHEMBL756302

CO[C]1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 4/20 0.41
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ALOX15 P16050 3/20 0.41
POLB P06746 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
BCHE P06276 1/20 0.41
PTPRC P08575 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
PTPN1 P18031 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693109 0.76 LMNA (0.41) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL217367 0.76 LMNA (0.38) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL10435815 0.73 SETD7 (0.37) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL5077508 0.71 LMNA (0.34) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL7635858 0.70 LMNA (0.33) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL3769766 0.70 MEN1 (0.55) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL1161991 0.67 LMNA (0.46) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL34469386 0.67 LMNA (0.46) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL217947 0.67 LMNA (0.46) LMNAALDH1A1MAPTKDM4EMEN1
SCHEMBL8079468 0.67 LMNA (0.41) LMNAALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019196720-A1 ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国科学院上海药物研究所 2019-10-17 WO claimed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP claimed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US claimed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP claimed
CN-110799868-B Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device 富士胶片株式会社 2022-02-22 CN disclosed
US-11230669-B2 Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2022-01-25 US disclosed
US-20200109333-A1 LIQUID CRYSTAL FILM, OPTICAL LAMINATE, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed
CN-110799868-A Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device 富士胶片株式会社 2020-02-14 CN disclosed
WO-2019196720-A1 ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国科学院上海药物研究所 2019-10-17 WO disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
EP-2235072-B1 USE OF POLYOLEFINS HAVING ISOTACTIC STRUCTURAL ELEMENTS IN FLOORING MATERIALS EVONIK DEGUSSA GMBH (DE) 2016-04-20 EP disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
WO-2008111685-A1 LIQUID CRYSTAL COMPOSITION, RETARDATION PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND PROCESS FOR PRODUCING RETARDATION PLATE FUJIFILM CORPORATION (JP) 2008-09-18 WO disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP disclosed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US disclosed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP disclosed