SCHEMBL5693445

SCHEMBL5693445

CC=CNC(=O)OCCCc1cc(-n2nc3ccc(C(F)(F)F)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 1/20 0.32
NAAA Q02083 1/20 0.31
MET P08581 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7144226 0.89 ALOX5 (0.35) GAANPSR1MET
SCHEMBL5693441 0.88 GAA (0.38) GAANPSR1NAAAMET
SCHEMBL3884142 0.85 GAA (0.32) GAA
SCHEMBL7145809 0.83 GAA (0.47) GAANPSR1
SCHEMBL5693420 0.83 GAA (0.35) GAANPSR1
SCHEMBL5693423 0.82 ALOX5 (0.30) GAA
SCHEMBL3290027 0.81 GAA (0.35) GAA
SCHEMBL2639325 0.81 ALDH1A1 (0.34) GAANPSR1
SCHEMBL3288318 0.81 GAA (0.35) GAA
SCHEMBL768820 0.81 GAA (0.41) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1305320-B1 PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2006-05-31 EP disclosed
US-6677392-B2 USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-13 US disclosed
EP-1305320-A1 PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2003-05-02 EP disclosed
US-20020115753-A1 Photostable, silylated benzotriazole UV absorbers and compositions stabilized therewith RAVICHANDRAN RAMANATHAN (US) 2002-08-22 US disclosed
WO-2002012252-A1 PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-02-14 WO disclosed