Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693423 | 0.91 | ALOX5 (0.30) | LMNASMN1; SMN2ALOX5 | |
| SCHEMBL5693449 | 0.88 | ALDH1A1 (0.34) | LMNAMAPTSMN1; SMN2ALOX5KMT2A | |
| SCHEMBL13715027 | 0.83 | ALDH1A1 (0.34) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL13546033 | 0.83 | KDM4E (0.35) | LMNASMN1; SMN2POLBKMT2A | |
| SCHEMBL5693426 | 0.83 | FFAR4 (0.33) | LMNAALOX5CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL16182319 | 0.82 | FFAR1 (0.39) | — | |
| SCHEMBL2638398 | 0.81 | KDM4E (0.34) | LMNAMAPTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL6444240 | 0.81 | NPC1 (0.33) | LMNASMN1; SMN2CYP3A4ADORA3CYP2D6 | |
| SCHEMBL2637632 | 0.80 | TLR8 (0.34) | CYP3A4KCNH2CYP1A2CYP2D6KMT2A | |
| SCHEMBL5693420 | 0.78 | GAA (0.35) | LMNASMN1; SMN2ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305320-B1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SC HOLDING AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| US-6677392-B2 | USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-13 | — | — | US | disclosed |
| EP-1305320-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20020115753-A1 | Photostable, silylated benzotriazole UV absorbers and compositions stabilized therewith | RAVICHANDRAN RAMANATHAN (US) | 2002-08-22 | — | — | US | disclosed |
| WO-2002012252-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |