Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693420 | 0.91 | GAA (0.35) | SMN1; SMN2GAAALOX5LMNARECQL | |
| SCHEMBL5693454 | 0.88 | LMNA (0.32) | SMN1; SMN2ALOX5LMNAMAPTKMT2A | |
| SCHEMBL5693441 | 0.87 | GAA (0.38) | GAAMEN1KMT2AMET | |
| SCHEMBL5693422 | 0.82 | RAF1 (0.32) | SMN1; SMN2ALOX5LMNARECQLMEN1 | |
| SCHEMBL13546033 | 0.81 | KDM4E (0.35) | ALDH1A1SMN1; SMN2KDM4EGAALMNA | |
| SCHEMBL16182319 | 0.81 | FFAR1 (0.39) | — | |
| SCHEMBL13715027 | 0.80 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6444240 | 0.80 | NPC1 (0.33) | SMN1; SMN2KDM4ELMNA | |
| SCHEMBL2638398 | 0.80 | KDM4E (0.34) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL5693423 | 0.79 | ALOX5 (0.30) | ALDH1A1SMN1; SMN2GAAALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305320-B1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SC HOLDING AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| US-6677392-B2 | USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-13 | — | — | US | disclosed |
| EP-1305320-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20020115753-A1 | Photostable, silylated benzotriazole UV absorbers and compositions stabilized therewith | RAVICHANDRAN RAMANATHAN (US) | 2002-08-22 | — | — | US | disclosed |
| WO-2002012252-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |