SCHEMBL5693486

SCHEMBL5693486

Br[Ni]Br.Cc1cccc(C)c1N=CC=Nc1c(C)cccc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
MEN1 O00255 1/20 0.38
HSP90AA1 P07900 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
TRPA1 O75762 2/20 0.34
ALDH1A1 P00352 4/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4350537 0.91 ATM (0.43) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL4350534 0.91 ATM (0.43) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL5591194 0.88 ATM (0.41) ATMMEN1HSP90AA1KMT2ACYP2A6
Bromide SCHEMBL5587158 0.86 ATM (0.40) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL17591505 0.80 MEN1 (0.36) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL25847142 0.77 ATM (0.38) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL7091923 0.77 ALDH1A1 (0.38) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL10890032 0.76 MEN1 (0.36) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL10890035 0.76 MEN1 (0.36) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL5587268 0.75 GABRA1 (0.39) ATMMEN1HSP90AA1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237461-B1 PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-03-18 EP disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
US-10787545-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-29 US disclosed
US-20200262983-A1 PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
US-10717826-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-21 US disclosed
EP-3233974-B1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
US-10472447-B2 Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-12 US disclosed
US-10465018-B2 Process for the preparation of a polyolefin having one or multiple end-functionalized branches SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-05 US disclosed
US-10450388-B2 Process for the preparation of a branched polyolefin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-22 US disclosed
EP-3034544-B1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-16 EP disclosed
WO-2016097203-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097204-A1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097208-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034544-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034546-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed