Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350534 | 0.95 | ATM (0.43) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL4350537 | 0.95 | ATM (0.43) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL5591194 | 0.92 | ATM (0.41) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL5693486 | 0.86 | ATM (0.38) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL17591505 | 0.84 | MEN1 (0.36) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL7091923 | 0.81 | ALDH1A1 (0.38) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL25847142 | 0.81 | ATM (0.38) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL10890035 | 0.79 | MEN1 (0.36) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL10890032 | 0.79 | MEN1 (0.36) | ATMMEN1HSP90AA1KMT2ACYP2A6 | |
| SCHEMBL5587268 | 0.79 | GABRA1 (0.39) | ATMMEN1HSP90AA1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237461-B1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2026-03-18 | — | — | EP | disclosed |
| EP-3034545-B1 | A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-11-04 | — | — | EP | disclosed |
| US-10787545-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-09-29 | — | — | US | disclosed |
| US-20200262983-A1 | PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-20 | — | — | US | disclosed |
| US-10717826-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-07-21 | — | — | US | disclosed |
| EP-3233974-B1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-02-19 | — | — | EP | disclosed |
| US-10472447-B2 | Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-12 | — | — | US | disclosed |
| US-10465018-B2 | Process for the preparation of a polyolefin having one or multiple end-functionalized branches | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-10450388-B2 | Process for the preparation of a branched polyolefin | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-22 | — | — | US | disclosed |
| EP-3034546-B1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| WO-2016097203-A1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| EP-3034544-A1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034546-A1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034545-A1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034547-A1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| EP-1519752-A1 | USE OF CETP INHIBITORS AND ANTIHYPERTENSIVE AGENTS AS WELL AS OPTIONALLY HMG COA REDUCTASE INHIBITORS | Pfizer Products Inc. (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004004777-A1 | USE OF CETP INHIBITORS AND ANTIHYPERTENSIVE AGENTS AS WELL AS OPTIONALLY HMG COA REDUCTASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | ACHE 3995/4885ATM 3933/4885MEN1 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.