Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952965 | 0.91 | IDO1 (0.49) | IDO1LMNAAGTR1CYP1A2MEN1 | |
| SCHEMBL5694034 | 0.87 | MEN1 (0.43) | IDO1LMNAAGTR1CYP1A2MEN1 | |
| SCHEMBL5595885 | 0.83 | CYP1A2 (0.61) | IDO1LMNAAGTR1CYP1A2MEN1 | |
| SCHEMBL5878268 | 0.83 | CYP1A2 (0.61) | IDO1LMNAAGTR1CYP1A2MEN1 | |
| SCHEMBL7969377 | 0.79 | IDO1 (0.53) | IDO1LMNAAGTR1CYP1A2MEN1 | |
| SCHEMBL26654 | 0.75 | IDO1 (0.69) | IDO1LMNAGAAMAPTHTT | |
| SCHEMBL13595479 | 0.74 | CA1 (0.54) | KMT2AHTTTSHRKDM4E | |
| SCHEMBL13595470 | 0.74 | CA1 (0.54) | KMT2AHTTTSHRKDM4E | |
| SCHEMBL13108196 | 0.74 | CA1 (0.54) | KMT2AHTTTSHRKDM4E | |
| SCHEMBL10587310 | 0.74 | CA1 (0.54) | KMT2AHTTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653945-A2 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2006-05-10 | — | — | EP | disclosed |
| WO-2004113289-A2 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2004-12-29 | — | — | WO | disclosed |