Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956663 | 0.86 | IDO1 (0.54) | IDO1TAAR1LMNASMN1; SMN2GAA | |
| SCHEMBL5878268 | 0.83 | CYP1A2 (0.61) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| SCHEMBL5595885 | 0.83 | CYP1A2 (0.61) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| SCHEMBL3952965 | 0.81 | IDO1 (0.49) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| SCHEMBL5696521 | 0.80 | IDO1 (0.50) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| SCHEMBL5694073 | 0.79 | IDO1 (0.46) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10411195 | 0.79 | IDO1 (0.51) | IDO1TAAR1LMNAAGTR1CYP1A2 | |
| SCHEMBL7312106 | 0.78 | IDO1 (0.50) | IDO1TAAR1LMNASMN1; SMN2GAA | |
| SCHEMBL26654 | 0.77 | IDO1 (0.69) | IDO1TAAR1LMNASMN1; SMN2GAA | |
| SCHEMBL17950799 | 0.77 | LMNA (0.67) | IDO1LMNAAGTR1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274715-B1 | SEMISYNTHETIC MACROLIDES, USEFUL IN BACTERIAL INFECTIONS TREATMENT AND PREVENTION, HAS LESS POTENTIAL FOR DEVELOPING RESISTANCE, IMPROVED OR MODIFIED PROFILES OF DESIRED GRAM-NEGATIVE ACTIVITY | ABBOTT LABORATORIES | 2001-08-14 | — | — | US | disclosed |