Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694073 | 0.87 | IDO1 (0.46) | MEN1KMT2AIDO1LMNAAGTR1 | |
| SCHEMBL3952965 | 0.84 | IDO1 (0.49) | MEN1KMT2AIDO1LMNAAGTR1 | |
| SCHEMBL5595885 | 0.80 | CYP1A2 (0.61) | MEN1KMT2AIDO1LMNAAGTR1 | |
| SCHEMBL5878268 | 0.80 | CYP1A2 (0.61) | MEN1KMT2AIDO1LMNAAGTR1 | |
| SCHEMBL7969377 | 0.76 | IDO1 (0.53) | MEN1KMT2AIDO1LMNAAGTR1 | |
| SCHEMBL26654 | 0.72 | IDO1 (0.69) | IDO1LMNAGAAMAPTHTT | |
| SCHEMBL694510 | 0.70 | IDO1 (0.56) | IDO1LMNAGAAMAPTALDH1A1 | |
| SCHEMBL7956663 | 0.68 | IDO1 (0.54) | MEN1KMT2AIDO1LMNAGAA | |
| SCHEMBL3655669 | 0.67 | IDO1 (0.53) | IDO1LMNAABCB1TAAR1CHRM2 | |
| SCHEMBL585111 | 0.67 | IDO1 (0.62) | IDO1LMNAGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653945-A2 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2006-05-10 | — | — | EP | disclosed |
| WO-2004113289-A2 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2004-12-29 | — | — | WO | disclosed |