Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694043 | 0.82 | SLC29A1 (0.38) | LMNA | |
| SCHEMBL5908160 | 0.82 | POLG (0.39) | — | |
| SCHEMBL5694044 | 0.78 | POLG (0.38) | POLB | |
| SCHEMBL5694287 | 0.78 | POLB (0.34) | POLB | |
| SCHEMBL5694161 | 0.77 | LMNA (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL21539912 | 0.74 | ALDH1A1 (0.45) | LMNAPOLBKDM4E | |
| SCHEMBL5908156 | 0.74 | TYMS (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL5694113 | 0.74 | POLB (0.42) | LMNAPOLB | |
| SCHEMBL5694389 | 0.74 | DNMT1 (0.40) | LMNAPOLB | |
| SCHEMBL17860588 | 0.72 | ADORA1 (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645561-A1 | METHOD OF SYNTHESIZING CYCLIC BISDINUCLEOSIDE | Mitsui Chemicals, Inc. (JP) | 2006-04-12 | — | — | EP | disclosed |