Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228223 | 0.88 | CES2 (0.64) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL31633615 | 0.88 | CES2 (0.64) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL1831093 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL19993973 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL27505714 | 0.82 | L3MBTL1 (0.61) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL5242228 | 0.81 | KDM4E (0.56) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL14609300 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL9221780 | 0.81 | CES2 (0.55) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL29289773 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL29576494 | 0.80 | KDM4E (0.68) | ALDH1A1CES2CES1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112118830-B | Solid dosage forms with high active agent loading | 比利时胶囊公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115697336-A | Pharmaceutical preparation and use thereof | 奥尔德拉医疗公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-112118830-A | High active agent loading solid dosage forms | 比利时胶囊公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-109503469-B | Preparation method of 2-acetylpyridine | 浙江理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110996913-A | Novel oral formulation of belinostat | 欧恩科斯欧公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-109503469-A | A kind of preparation method of 2- acetylpyridine | 浙江理工大学 | 2019-03-22 | — | — | CN | disclosed |
| EP-1643948-A1 | DIFFUSION LAYER MODULATED SOLIDS | Pharmacia & Upjohn Company LLC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050042291-A1 | Diffusion layer modulated solids | HAWLEY MICHAEL (US) | 2005-02-24 | — | — | US | disclosed |
| WO-2005004763-A1 | DIFFUSION LAYER MODULATED SOLIDS | PHARMACIA & UPJOHN COMPANY LLC. (US) | 2005-01-20 | — | — | WO | disclosed |