SCHEMBL1108095

SCHEMBL1108095

CC(=O)OCCOCOc1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
NOTUM Q6P988 1/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
THRB P10828 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
PTPN1 P18031 1/20 0.42
TSHR P16473 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694355 0.87 TDP1 (0.56) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL13683036 0.80 TDP1 (0.48) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL16981961 0.79 L3MBTL1 (0.52) TDP1L3MBTL1ALDH1A1KDM4ELMNA
O-Xylene SCHEMBL9686891 0.77 ALDH1A1 (0.68) TDP1ALDH1A1LMNASMN1; SMN2THRB
SCHEMBL15946382 0.76 L3MBTL1 (0.55) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL12301118 0.76 DRD2 (0.46) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL10030191 0.76 TDP1 (0.55) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL10030193 0.74 TDP1 (0.53) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL17921568 0.73 THRB (0.56) TDP1L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL7872986 0.73 TDP1 (0.49) TDP1ALDH1A1KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7876403-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090180059-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-07-16 US disclosed
US-20090040435-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed
US-20080225210-A1 Optical Compensation Film, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed