⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490961 | 0.76 | — | — | |
| SCHEMBL3279254 | 0.76 | — | — | |
| SCHEMBL4333144 | 0.76 | — | — | |
| SCHEMBL79940 | 0.76 | — | — | |
| SCHEMBL1378679 | 0.73 | RAB9A (0.42) | — | |
| SCHEMBL28914669 | 0.71 | ACHE (0.60) | — | |
| SCHEMBL4712807 | 0.71 | RAB9A (0.67) | — | |
| SCHEMBL4712805 | 0.71 | RAB9A (0.67) | — | |
| SCHEMBL5106488 | 0.70 | LMNA (0.42) | — | |
| SCHEMBL30715313 | 0.69 | HDAC8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030036541-A1 | Beta-lactamase inhibiting compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-02-20 | — | — | US | claimed |
| JP-2002542249-A | — | — | 2002-12-10 | — | — | JP | claimed |
| US-6407091-B1 | CEPHALOSPORIN DERIVATIVES; TREATING MICROBIAL AND ANTIBIOTIC RESISTANCE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-06-18 | — | — | US | claimed |
| EP-1169323-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | Research Corporation Technologies, Inc (US) | 2002-01-09 | — | — | EP | claimed |
| WO-2000063213-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| EP-1359153-B1 | Beta-lactamase inhibiting compounds | RES CORP TECHNOLOGIES INC (US) | 2006-06-21 | — | — | EP | disclosed |
| US-6906054-B2 | Compositions for inhibiting beta-lactamase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1359153-A1 | Beta-lactamase inhibiting compounds | Research Corporation Technologies, Inc (US) | 2003-11-05 | — | — | EP | disclosed |
| US-20030036541-A1 | Beta-lactamase inhibiting compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-02-20 | — | — | US | disclosed |
| US-6407091-B1 | CEPHALOSPORIN DERIVATIVES; TREATING MICROBIAL AND ANTIBIOTIC RESISTANCE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1169323-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | Research Corporation Technologies, Inc (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000063213-A1 | BETA-LACTAMASE INHIBITING COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-10-26 | — | — | WO | disclosed |