Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941251 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL17288936 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL5134897 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL830414 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL8166558 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL6946790 | 0.74 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL1903577 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL10619292 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL473081 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL7639 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663954-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005014530-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2005-02-17 | — | — | WO | disclosed |