Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770005 | 0.86 | KMT2A (0.69) | ALDH1A1HPGDGAAALOX12HTT | |
| SCHEMBL11794982 | 0.82 | POLB (0.60) | ALDH1A1HPGDGAAALOX12HTT | |
| SCHEMBL11770050 | 0.81 | ALOX12 (0.72) | ALDH1A1HPGDGAAALOX12HTT | |
| SCHEMBL11546965 | 0.80 | ALDH1A1 (0.84) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL24742586 | 0.80 | HPGD (0.60) | ALDH1A1HPGDGAAALOX12HTT | |
| SCHEMBL10488599 | 0.79 | ALDH1A1 (0.81) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL2434485 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL6816667 | 0.78 | ALDH1A1 (0.84) | ALDH1A1HPGDGAAALOX12SMN1; SMN2 | |
| SCHEMBL11771677 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL5454882 | 0.77 | ALDH1A1 (0.69) | ALDH1A1HPGDGAAALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975433-A | ANTIDEPRESSANT, PARASITICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-08-17 | — | — | US | claimed |
| US-3969532-A | 1-Aryl-3-(2-hydroxyethyl) thioureas for treating depression | THE DOW CHEMICAL COMPANY (US) | 1976-07-13 | — | — | US | claimed |
| EP-1228172-B1 | SUBSTITUTED LINEAR THIOUREA COMPOUNDS AS ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2006-05-31 | — | — | EP | disclosed |
| US-3975433-A | ANTIDEPRESSANT, PARASITICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3975433-A | ANTIDEPRESSANT, PARASITICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3975433-A | ANTIDEPRESSANT, PARASITICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3969532-A | 1-Aryl-3-(2-hydroxyethyl) thioureas for treating depression | THE DOW CHEMICAL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |