Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814747 | 0.83 | HPGD (0.53) | ALDH1A1MAPTSMN1; SMN2HPGDPOLB | |
| SCHEMBL5450035 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2TDP1HPGD | |
| SCHEMBL5695271 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2HPGDPOLB | |
| SCHEMBL5663443 | 0.77 | KMT2A (0.51) | ALDH1A1MAPTSMN1; SMN2HPGDGAA | |
| SCHEMBL5450418 | 0.75 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2TDP1HPGD | |
| SCHEMBL29752141 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2TDP1HPGD | |
| SCHEMBL4141161 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2TDP1HPGD | |
| SCHEMBL21815078 | 0.75 | GAA (0.47) | SMN1; SMN2HPGDPOLBGAAHTT | |
| SCHEMBL5448159 | 0.75 | ALDH1A1 (0.66) | ALDH1A1MAPTTDP1HPGDPOLB | |
| SCHEMBL11793713 | 0.74 | POLB (0.73) | ALDH1A1MAPTPOLBGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |