Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695396 | 1.00 | MAPT (0.59) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL3745130 | 0.80 | RPS6KA3 (0.71) | MAPTXDHTDP2CASP7CASP9 | |
| SCHEMBL19462942 | 0.79 | MAPT (0.61) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL5695409 | 0.77 | MAPT (0.62) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL5695429 | 0.77 | MAPT (0.62) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL9094449 | 0.76 | XDH (0.44) | MAPTHTTMEN1KMT2AXDH | |
| SCHEMBL5695444 | 0.76 | TYR (0.74) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL29226048 | 0.76 | NPC1 (0.63) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL22625308 | 0.76 | MAPT (0.61) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL5695416 | 0.76 | TYR (0.74) | MAPTHTTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | claimed |